SAN JOSE, Calif.—For the primary time in her criminal-fraud trial, Elizabeth Holmes on Tuesday took intention on the most critical allegations made towards her by prosecutors, providing a story of herself as a well-intentioned if inexperienced entrepreneur who had some success in her effort to rework healthcare.

Ms. Holmes’s full day of testimony was her longest but in her protection towards 11 expenses of fraud and conspiracy referring to her time working defunct startup Theranos Inc., which collapsed in 2018. It adopted 11 weeks of testimony supporting the prosecution’s case that Ms. Holmes bumped into bother making an attempt to construct her blood-testing firm and knowingly misled buyers and sufferers about her know-how’s capabilities.

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